منابع مشابه
Amiodarone and post-MI patients.
Amiodarone is a viable drug for preventing sudden cardiac death, particularly during the first year after MI. If larger trials confirm the aforementioned prospective trials of Ceremuzynski et al, Cairns et al, and the BASIS trial, the efficacy of amiodarone would outweigh the risk of its side effects during the first year after MI. Based on the long-term observation from the BASIS trial, the du...
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Wnt signaling plays an important role in developmental and stem cell biology. To test the hypothesis that temporary inhibition of Wnt signaling will enhance granulation tissue and promote angiogenesis in tissue repair, we employed a recently characterized small molecule Wnt inhibitor. Pyrvinium is an FDA-approved drug that we identified as a Wnt inhibitor in a chemical screen for small molecule...
متن کامل764 Amiodarone and Post - MI Patients
Survivors of acute myocardial infarction (MI) remain at risk of sudden cardiac death after being discharged from the hospital. In these patients, frequent premature ventricular contractions (PVCs) and depressed ventricular function herald sudden cardiac death.1-3 These observations triggered the idea that if PVCs were suppressed by antiarrhythmic agents, then sudden cardiac death could be avert...
متن کاملDelayed erythropoietin therapy reduces post-MI cardiac remodeling only at a dose that mobilizes endothelial progenitor cells.
We examined the cardiac effects of chronic erythropoietin (EPO) therapy initiated 7 days after myocardial infarction (MI) in rats. A single high dose of EPO has been shown to reduce infarct size by preventing apoptosis when injected immediately after myocardial ischemia. The proangiogenic potential of EPO has also been reported, but the effects of chronic treatment with standard doses after MI ...
متن کاملRegulatory Role of Dendritic Cells in Post-Infarction Healing and Left Ventricular Remodeling Running title: Anzai et al.; Dendritic cells in LV remodeling after MI
Division of Cardiology, Dept of Med, Dept of Microbiology & Immunology, Dept of Pathology, Keio University School of Med, Tokyo, Japan; Dept of Cardiovascular Med, National Cerebral & Cardiovascular Center, Osaka, Japan; Core Research for Evolutional Science & Technology (CREST), Japan Science & Technology Agency (JST); Cardiovascular Center, International University of Health & Welfare Mita Ho...
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ژورنال
عنوان ژورنال: Clinical Cardiology
سال: 1993
ISSN: 0160-9289,1932-8737
DOI: 10.1002/clc.4960161406